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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '729b726a071504d84a60fb5a134fcaa97ca9119abde097219a4609a8d9c2dc25' 
  AND token = 'IUtAG8NZb3AoPVEw92j44eqfzpcQoJg3rdoVvqjLru0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}