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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '760670adf0b2a2db07faa9b2d4c08e39cf6c59f04d4b89f000b2878c54f14549' 
  AND token = 'FoWhn4RSfyr/V9Ql3X/sdjxhxLt1xoJ+qAriukeVbV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}