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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b70eb032a97cd04793301fa14858ba55cf5ef03729b869a4d11b2045d79bda' 
  AND token = 'RIk2Ie+AqbCAUOoTLVTI0Seug6vhXoRdCwKrQTDdRvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}