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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234a0e8e129f39ec54a4b4905d0ca85d143fba24c233d7e0c59d0d1a3acab822' 
  AND token = 'EbLkrscnfTU4RWj/qLv/BqO4uIFxh0mGup6Vr+UWQcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}