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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e16644cd9f6ca59e46f5d183368838776a7fb19d5e5a060fbc2200c6e2399a0' 
  AND token = '+0HwstgEEqIGLI/aLDB8X9DSTZuanuyltZT8LPd1KMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}