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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fee3c5834c9be4eef4d2b4b649753bb388ab33a5ad82e530cbde8c684b9e6f7' 
  AND token = 'gZQ4TydOJ3taIDHrUbFNFzVjca3SaT4CwTDbpEs9KeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}