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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54927060ace614a5047cd22a98c99b9fbeffd47614e89701e17f958affb34db4' 
  AND token = '6kIp+zyUU3NA1zWFHIrrtxezj1VGtpFVFisk/U+vQMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}