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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8721bcc6fd95371d679fe8ecf6de51ac852beb69aea6e72da5343865c8db785' 
  AND token = '9UuuF6ZeUq+NQ55DQnkeA5ym0suFJPOobbctMJwdkag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}