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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc33a271af0aacb73d8cac727bc10c30dd0671feaa1dfd05647cee421f950995' 
  AND token = 'Wmih2PuOD5n93nyNvPYfNy41krr5I/VPtkI6SvcDBFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}