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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '942f9dad8e5c41e1186b04b07e32d4ec818dfd276bad68d8cb9e17313c35f5a8' 
  AND token = 'tp8dgelU12Px/uClXCT9hGsGK6fPPagzQ1Qmwfl2ZW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}