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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ae5147fb3f6d9bf01f376bbddef1f2afe76a6415e8f7db46b51517d6e13df2' 
  AND token = 'mQBGooXwTTODDwIeaU+rYUCJRqB7S6ik1cfyvsHXnfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}