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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc3d257175971308dbd1f88d12be86877976668d570e3303665a809183a25844' 
  AND token = 'ivmWLSfmn8okdlClH9WOx14J/v0IxqAN8AZ2yYvpQcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}