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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14522889e00558e8730f0b2fb794ba25e20731adcf29459c7c7c73a12c370b5c' 
  AND token = '2cle6Z1l6/LU65w8aBGpmI89IcjaFjARFfTMsPzUKA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}