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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66762f3a9da318446c2fbc534f2a29fc69ba00b1cc60660234e8c2b53a8a914a' 
  AND token = 'otJIuTMZWtIYapbfWdWoPpp5Ndw0XXbYgldRtDNEoSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}