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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c5dd172229903c1aaff9f5a0403a4a502ecb1652f9c433ed5bb6df46afba5e' 
  AND token = 'TBsqytvwKYXfTm3iAATFuLAhYQSQ6IquUumDun45uu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}