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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3224eea6d1806cc49f03e1076868ba22c2d2dc3078b0a4a3d6310d3c3f77ed65' 
  AND token = 'tsGuYl2hVlFwB/Nvrjm9mBcB6Pi1S+Mj30OpkenWnDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}