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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fc35ce7b66aa3199f396519f9410f235e4de9f5f17dfca620fc07b566b0e482' 
  AND token = 'AKWu+6bHPkjWd8SU0HY/mFYTxbOvDJyaAjDc8ktP+z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}