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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c46fd05ab702d4a5b266f7e7963038827840bde9d4bb4a330bb7c6bbfc3029' 
  AND token = 'ZgsbB4tJWLfvD2oNJ74d0iBaDyVLeFfIBj3OyXwlqX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}