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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc93aa9404db32c08512a2457d032e1175a6811c9c764b1576f98c5d3c58337' 
  AND token = 'ERe8KzB7Nqtpmvy7NEKF8aMC2EjkMQoKAO0Hj7b7WYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}