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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c83b145c05dc2d998e2ba91127ca30249bca72ac33ccf835de85d79f66e84945' 
  AND token = 'wLm139rWHZuszoTvCYHWN95xMW+WnNDlrpzMzeKQ/bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}