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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189258157a903aa99fbbd721fe185b241e44d0d94f9cbfed030389a890749deb' 
  AND token = 'HZ8EGoD8RekQ2JZ0pBhBAUp1gpRflyU3/MpTc2q7d3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}