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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ede0b36e926f8b4f6e0dd3769b5729bd99ed15d967a4b258b9f4d51bde62951' 
  AND token = 'WEv78sf7Cgo/mwojuRZMoFeeQ8JPyGFbxqSt0U/5I+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}