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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a074133d4a2ffda218c65a12c659d3e99058032b0c01b1c459b2f22a73cf0a64' 
  AND token = 'r8Vz2OClewWrVuTAiNcSvi2gohC0VVndclL6dM2MsdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}