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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42b9778fe7f403d79c0c53251dcbab8a42c82641c7b10980340e86f0c311083' 
  AND token = 'dwsbp4sMUAWomBaukZ669kEDrZ3TJzxgeLIkWhG+Pag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}