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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1121d627627920ec411a43901b7f13c12b330efcae98d7dba6db5bfa4e5a9c1' 
  AND token = '8WHIPRKsx8rMg6zeWwflbuohBKWB6hveaqghjCiMOzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}