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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cc8c1baac7c44adc2276c9c4dd469ccd6786842425a34e0ac96e33a14597879' 
  AND token = '+v5ThGY9GTb/Uvy8t+dPpAG9UHv+aWVRkA6Uedg7G+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}