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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c38da834ca021531ad836f1e718a781f42b856e9f0ab80f80825f9be363186e' 
  AND token = 'Sxe6638c1Md/DPQOGBAMXPHpndYuCUMrIV2brLJ5gYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}