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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a4a189566a03bd29d77b0c8a5cb74bff5bc35f207a6248a870e78411b79b3a' 
  AND token = 'McCMpvPuNN2t+qPU0uymqS8dVSJf1uafQjdsThYW6Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}