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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6465f61f643290d05fa543a5c5b4f9f6147397be920ff3b3d14468ba70638f15' 
  AND token = 'eY2286MWMLgvTPdyYvP6lAEsYniizMpbSZ6/ZGYN64E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}