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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef1c24cdf6787d00f484b2c6a71debe1cb25eddeb932fffb00821728efcba39' 
  AND token = 'Rd6dHpZOVdrxXx0dYaCPcPhogDYtqVXr6EY85cmTkMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}