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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e847aced3b84674be403f7f021e03b7cb014cb33ba23d2a50b1258bd497aff1' 
  AND token = 'bKkUsoxRyNMdmsBStPT/Gj/sNrxtsUCH02s7ct12QzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}