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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7166740400aeac79b9e9f1ff319a6b8aca514285557e601d3ca31c7cd970952' 
  AND token = 'EMyATIy0ZBl7Cso93s3aDDgbdgahprcjTI1Hx5WOFmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}