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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824310c6775d6b28c450eec9d97ecea0c9ddc07ed0e02362ce692bf6307f716e' 
  AND token = 'A0hpk1GyDOfGitg4cyStnXaQeh6NzsQhQO3ZfK1+PvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}