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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a27fb12d52d801b5d1d1a91645888f1f328a407e89f7bc5b1ee93cc1e26c6607' 
  AND token = 'XoDIP6DhAWg9R5qDt+NIBiRRq+4kysqGqMzkD9FHO3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}