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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '430791ed61db5af40cce954626c22f1fd4d0d277465986c6bc376546247260af' 
  AND token = 'MxHH4gn4SL0HpYinMqvsoNPr0v4hIRdZk1SSgy0Otk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}