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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adf07430f792e2d8025884254ad56f21add7b3fabe0cb5bff0c0cd206379b7e2' 
  AND token = 'oRzekEQEp/W9OxWQkA8rYeKti9yj7SjY/+sl0+Lexn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}