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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440523e9e51109a3fd64239f3d5780143103f45a855befa50f3e19a7125af7ad' 
  AND token = 'zcSlKcC5So5RnKbX+F70wiReETOyxUlR13PiCgGbV+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}