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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '890952cee975b5a1fd0aea25fbe68c9f7b180a3d903568fc1dc6f3f5059179bd' 
  AND token = 'varNnm66CiwjZcVl/mdZX0GMARdSqYxy8DGPqN2C8Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}