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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a6fe7b9c16647aaced41d0a297aad957ef0a23ce3755aa1898d8a99580719d' 
  AND token = 'aWPwM1l6CoK2/RV9KuF1CxaE+ib+qe/K1qpfpzW0lyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}