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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5686845778c2a46a6e9cafdfd5b947eef323ee7c2ccfa3dc5a2b387b691716d7' 
  AND token = '7mzjjBkTeJraZmqcsXDK9oePN1MRsP9kMg8X2rm4fL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}