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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51a70501a1e3542ded959afd3c0342780487ed9a5f3912f6a381e88ec1de7cc5' 
  AND token = '2Y5uzFxB7HSwr9S3FPfKjDeGLZmtxuDt3Nwa9TxVcig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}