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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9cf72900bf5f29ca3bf797387741e08d30aefd024907a0e995ce3476654f9fd' 
  AND token = '3xUYTe+w6pyqntUR9AZ1v6KgWMbib9KzLo63v8pY4IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}