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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a142971ba41f0d5c275a72e52f3f6a1efae4e8293c96c0499cbbf9cac717c3b' 
  AND token = 'ej9/x9T0dqB/cBHTK3YAkhMHUtCpyT+mScAiL+ZdDtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}