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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e267b74b3a1c0c61a9e58503dfd85c0ff901b84cb70a594fba2e53a96111d91' 
  AND token = 'gqnQeKNtuQxY/to1V9JZEvTcsyFidWTtO05x2HaBtN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}