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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fada680b6d35aa88b67d5959a129d817142c6dd9fbb8db73c426c428eabc74c' 
  AND token = '/Gg90O9iWBUEtlPYn0nSNl7iQHF3FQU68avz512CA6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}