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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c11b7e6bac4b9580929f15b20dfcaf627bcd397b0c6b60343f14d95f3d4fca54' 
  AND token = '1LvJRcmCxFMrAD2bB0zjAk5lkQViBJ32dqrDgzzp3Jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}