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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4b5e85e03b7c1c4a8b1e719491dc95800c438258ba8944eec0e2efb3e8a472' 
  AND token = 'zUZYCHammvuRxPoUR07HD7vh15HBsUj0jKzwtSKGb3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}