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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdb4a54185e50ae0e99c9e12b77a34d2fe1b2d3edd22b14348fac7203c1aad4f' 
  AND token = 'GlPnPBj4YP2MeGXOkjdD5dvbCsANW4Xll9Rc9edSDQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}