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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67f2380a59e8ce19ba3a082ddaa189a614fc800e8ba7be9cbf9f8a3c0bc544d6' 
  AND token = 'xppQe+rB4SWfB/I9GHCHwbsWpE3O0Lb2hWjLDFTKKtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}