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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acb41f5e81750c445d6bbb5b2f108de132074bde3240490e2eaf2dcfef99c3b8' 
  AND token = 'Yll9Jk85KGtkWTVX3WXmbKM9TD+grF/ZQcX/iSef+Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}